Topicaine

Q: What is TOPICAINE ®?

A: TOPICAINE ® is a gel microemulsion delivery system containing lidocaine 4% in a non -greasy formulation; with skin permeation enhancers and soothing agents.

Q: What is it for?

A: It is specially formulated to penetrate intact skin, for the prevention and relief of pain. Applied 30-60 minutes in advance, it can be used to numb the skin prior to cosmetic and medical procedures that cause moderate pain. Initially developed for electrolysis, it has been found useful for: waxing, laser hair removal, laser skin resurfacing, permanent make-up, tatoos, blood extractions, injections and vaccines (wonderful for children's vaccinations), dialysis procedures, collagen injections, hair transplants, removal of ingrown nails and more. It can also relieve the pain caused by minor burns and insect bites.

Q: What makes this product unique?

A: Each of the following terrific benefits (not to mention all of them together!):
  • the combination of maximum strength lidocaine (4%) with safe and effective skin permeation enhancers provides effective numbing action, with rapid onset and long duration.
  • non-greasy formula is easy to remove and does not interfere with beauty procedures. Oily formulations (such as other products in the market) can interfere with the efficacy of electrolysis, make cause pigment migration during permanent make up, and impede adhesion of the wax to hair during waxing.
  • gel form is easy to apply and stays in place! Many anesthetics in the market are liquid and are not only ineffective but tend to get into areas where they cause trouble such as the eyes, nostrils, etc. With Topicaine ®, the application is very precise and convenient.
  • no prescription required, but maximum strength (4%) lidocaine allowed in the USA. This makes Topicaine ® much more affordable and convenient than EMLA ® cream (an Astra Pharmaceuticals prescription cream which is well known specially among plastic surgeons and some beauty professionals)
  • other qualities: self-preserving action, non-irritating, with skin soothing agents such as glycerin, jojoba oil and aloe vera oil.

Q: How thick does Topicaine ® need to be applied?

A: A moderately thick layer works best. It is obtained applying 0.3-0.4 grams of gel per 10 cm2 of skin. As an example, this means applying a dollop the size of a penny to cover the entire upper lip area (from the nostrils to the upper lip contour; area 20 cm2). Or a dollop half the size of a dime, to cover the eyebrow area.

Q: How long does it take to numb the skin?

A: As an average, the skin above the upper lip or or eyebrows areas will be numb enough to perform most procedures without discomfort, after 30 minutes of application. Other areas such as the legs or bikini may take longer, 45-60 minutes. Covering the gel with an occlusive film such as saran favors the penetration of the numbing agent into the skin.

Q: What degree of numbness is obtained?

A: The duration of application is the single most important factor in predicting the degree of numbness. The longer the application time, the deeper and more complete the degree of analgesia. For most patients, the application of Topicaine ® 30-60 minutes in advance, preferably covered with an occlusive film such as saran, will numb the skin enough to prevent discomfort caused by a variety of cosmetic and medical procedures.

Q: Does it work better under occlusion?

A: Yes, occlusion (with any film material such as cellophane, saran, Tegaderm or Flexi-film) promotes the penetration of the anesthetic into the skin. It is specially useful for areas with less skin blood supply like the legs.

Q: How many applications can be obtained from each of the different sizes?

Area of body

Area dimensions (in)

Avg amount required (grams)

Comments

Recommended Size of Topicaine

Lips

1x4

0.7-1

Unitdose (1 g); 10 g tube (10-12 treatments)

Bikini Area

8x3x2

8-10

Both sides

10 g tube (1 treatment); 30 g tube (3-4 treatments)

Whole face

10x7

10-15

30 g tube (2-3 treatments)

Upper legs

20x12

25-30

Each upper leg

4 Oz tube (x4 treatments)

Lower legs

12x12

20-30

Both lower legs

30 g tube (1 treatment), 4 Oz tube (4-5 treatments)

Back

20x15

35-40

4 Oz tube (x3 treatments)

Q: Can it be applied around the eyes?

A: It should not be applied inside the eyes, it is not an ophthalmic product. Contact with the eyes should be avoided. If contact with the eyes occurs, flush the eyes with saline solution or with water. It has been used to numb the skin below the lower eye lashes area for permanent make up, and since the skin is very thin in this area, usually good control of the pain is achieved after 7-10 minutes of application.

Q: Does it have to be removed before a beauty procedure?

A: It is not necessary to remove Topicaine ® before electrolysis or permanent make up. For waxing, it is recommended to wipe the area with a moist towelette.

Q: What are skin permeation enhancers?

A: These are substances that temporarily change the permeability of the stratum corneum, allowing other substances to cross this barrier more effectively. The permeation enhancers used in Topicaine ® are effective yet non irritating.

Q: Do I need a prescription to get Topicaine ®?

A: No prescription is necessary. It is an over the counter (OTC) pharmaceutical product. It contains the maximum strength of lidocaine allowed for topical use in the USA without a prescription.

Q: Is Topicaine® compatible with laser procedures?

A: Topicaine® ® is a translucent gel, with consistency and appearance similar to ultrasound gel. Topicaine® should be applied 30-60 minutes prior to the application of the laser, preferably under occlusion. Laser hair removal with the ruby laser or intense light devices, specially for darker skins (type III and above) can cause considerable discomfort which can be avoided with Topicaine®. Topicaine® does not contain chromophores or substances that could absorb the laser light. Topicaine® contains alcohol 35% so it is recommended that Topicaine® be removed prior to the application of the laser or that Topicaine® be covered with ultrasound or coupling gel before the application of the laser or intense light.


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